順天堂大学医学部附属順天堂越谷病院
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順天堂越谷病院 脳神経内科
スタッフの活動
研究業績(王 梅医師)
  1. Wang M, Hattori N, Matsumine H, Kobayashi T, Yoshino H, Morioka A, Kitada T, Asakawa S, Minoshima S, Shimizu N, Mizuno Y. Polymorphism in the parkin gene in sporadic Parkinson's disease. Annals of Neurology 45(5): 655-58, 1999.
  2. Wang M, Suzuki T, Kitada T, Asakawa S, Minoshima S, Shimizu N, Tanaka K, Mizuno Y, Hattori N. Developmental changes in the expression of parkin and UbcR7, a parkin-interacting and ubiquitin-conjugating enzyme, in rat brain. Journal of Neurochemistry 77: 1561-1568, 2001.
  3. Hattori N, Kitada T, Matsumine H, Asakawa S, Yamamura Y, Yoshino H, Kobayashi T, Yokochi M, Wang M, Yoritaka A, Kondo T, Kuzuhara S, Nakamura S, Shimizu N, Mizuno Y. Molecular Genetic Analysis of a Novel Parkin Gene in Japanese Families with Autosomal Recessive Juvenile Parkinsonism: Evidence for Variable Homozygous Deletions in the Parkin Gene in Affected Individuals. Annals of Neurology 44: 935-941, 1998.
  4. Hattori N, Matsumine H, Asakawa S, Kitada T, Yoshino H, Elibol B, Brookes A. J., Yamamura Y, Kobayashi T, Wang M, Yoritaka A, Minoshima S, Shimizu N, Mizuno Y. Point Mutations (Thr240Arg and Ala311Stop) in the Parkin Gene.Biochemical and Biophysical Research Communications 249: 754-758, 1998.
  5. Kobayashi T, Wang M, Hattori N, Matsumine H, Kondo T, Mizuno Y. Exonic deletion mutations of the parkin gene among sporadic patients with Parkinson's disease. Parkinsonism & Related Disorders 6(3): 129-131, 2000.
  6. Hattori N, Shimura H, Kubo S, Wang M, Shimizu N, Tanaka K, Mizuno Y. Importance of familial Parkinson's disease and parkinsonism to the understanding of nigral degeneration in sporadic Parkinson's disease. J Neuro Transm, 60: 101-116, 2000.
  7. Hattori N, Shimura H, Kubo S, Kitada T, Wang M, Asakawa S, Minashima S, Shimizu N, Suzuki T, Tanaka K, Mizuno Y. Autosomal recessive juvenile parkinsonism: A key to understanding nigral degeneration in sporadic Parkinson's disease. Neuropathology 20:S85-S90, 2000.
  8. Li X, Kitami T, Wang M, Mizuno Y, Hattori N. Single nucleotide polymorphism of parkin in sporadic Parkinson's disease: Association study between two polymorphisms (D/N394 and L/I272) of the parkin gene and sporadic Parkinson's disease. Parkinsonism & Related Disorders 11(8): 485-491, 2005.
  9. Tomiyama H, Li Y, Funayama M, Hasegawa K, Yoshino H, Kubo S, Sato K, Hattori T, Lu CS, Inzelberg R, Djaldetti R, Melamed E, Amouri R, Gouider-Khouja N, Hentati F, Hatano Y, Wang M, Imamichi Y, Mizoguchi K, Miyajima H, Obata F, Toda T, Farrer MJ, Mizuno Y, Hattori N. Clinicogenetic study of mutations in LRRK2 exon 41 in Parkinson's disease patients from 18 countries. Movement Disorders 21(8): 1102–1108, 2006.
  10. Hattori N, Wang M, Taka H, Fujimura T, Yoritaka A, Kubo S, Mochizuki H. Toxic effects of dopamine metabolism in Parkinson's disease. Parkinsonism & Related Disorders 15(1): S35-38, 2009.


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